Electron-capture dissociation ( ECD ) was developed in 1998 to fragment large proteins for mass spectrometric analysis.
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However, experiments about the duration of the digestion process showed that after 3 h there is enough material for successful mass spectrometric analysis.
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The peptides are then dissolved in a small amount of distilled water or further concentrated and purified using ZipTip Pipette tips and are ready for mass spectrometric analysis.
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Due to the rareness of the amino acid cysteine for most of the proteins the step of r & a does not effect any improvement of the mass spectrometric analysis.
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Mass spectrometric analysis is just one implementation of an effective extraction system development that was needed to cut the surgical site at the time of running the generated aerosol mass spectrometer.
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OK, after all of this discussion, I actually bothered to do a search . this article discusses mass spectrometric analysis of sodium-water solvation clusters formed during the sodium-water reaction.
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In contrast to the traditional MS methods, where the dye must be extracted from the fabric and the dye components are separated by chromatography prior to mass spectrometric analysis, the IR-MALDESI source allows for direct analysis of the dye from the fabric.
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He also worked on iodine speciation in seawater and porewaters, the separation of cerium from other rare earth elements in a classic example of redox behaviour; he has developed a precise mass spectrometric analysis method and made the first ever measurements of oceanic profiles for 10 rare earth elements.
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